Fraunhofer-Verbund Life Sciences
Fraunhofer-Verbund Life Sciences

Airway and Lungs

in vitro

efficacy safety model
X   A human airway mucosa tissue model for infection studies
X   3D lung tumor model for drug testing
X X P.R.I.T.-ALI Technology for testing airborne substances
X X Viral infection model in precision-cut lung slices
X X Isolated Perfused Rat Lungs
X X Airway epithelial cell model for efficacy studies with inhaled anti-inflammatory drugs
X X Immune receptor based reporter gene assay for detection of allergens and respiratory pathophysiology and pathogenesis

in vivo

efficacy safety model
X   Model of viral respiratory tract infection in BALB/c mice
X   Bleomycin induced systemic sclerosis in C3H mice
X   House Dust Mite (HDM) induced acute allergic asthma in BALB/c mice
X   Ovalbumin induced allergic asthma in huNSG mice
X   Ovalbumin induced allergic rhinitis in BALB/c mice
X   Viral respiratory infection mouse model
X   Bacterial respiratory infection rodent models
X   House dust mite (HDM)- induced severe chronic asthma modelCreate table
X   LPS - induced respiratory inflammation in rodents
X   Lipopolysaccharid-induced neutrophilic inflammation in marmosets
X   Subacute house-dust mite induced asthma modell in marmoset monkeys
X   Ovalbumin-induced acute asthma model in mice and rats
  X Tolerability studies in marmoset, rhesus, and cynomolgus macaque
  X Pharmacokinetic studies in marmosets and cynomolgus macaques