Muskel-Skelett-System

in vitro

efficacy	safety	model

in vivo

efficacy	safety	model
X		Collagen antibody induced arthritis (CAIA) in mice
X		Collagen induced arthritis (CIA) in mice
X		Fibroblast induced cartilage destruction in Balb/c mice
X		Fibroblast induced cartilage destruction in SCID mice
X		Pristane induced arthritis (PIA) in rats